Core-Sheath Nanofibers as Drug Delivery System for Thermoresponsive Controlled Release
نویسندگان
چکیده
منابع مشابه
A novel controlled release drug delivery system for multiple drugs based on electrospun nanofibers containing nanoparticles.
This study describes development of a novel controlled drug release system for multiple drugs, it consisted of Chitosan nanoparticles/PCL composite electrospun nanofibers with core-sheath structures. Two model agents' rhodamine B and naproxen were successfully loaded in the core and sheath region respectively. The behavior of these two agents demonstrated a good controlled release and temporali...
متن کاملElectrospun polymeric nanofibers for transdermal drug delivery
Conventional transdermal drug delivery systems (TDDS) have been designed for drug delivery through the skin. These systems use the permeability property of stratum corneum, the outermost surface layer of the skin. Applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...
متن کاملDrug Delivery: Controlled Release
Over the past decades, the treatment of illness has been accomplished by administering drugs to the human body via various pharmaceutical dosage forms, like tablets. These traditional pharmaceutical products are still commonly seen today in the prescription and over-the-counter drug marketplace. To achieve and maintain the drug concentration in the body within the therapeutic range required for...
متن کاملDesign and performance investigation of electrospun PVA nanofibers containing core-shell nanostructures for anticancer drug delivery
Objective: The purpose of this work was design and performance investigation of a nanocarrier based on magnetic nanofibers containing core-shell nanostructuresfor anticancerdrug delivery of daunorubicin (DAN) by measuring their drug release at different pH values. Methods: Fe3O4 nanoparticles and Fe3O4@SiO2core-shell nanostructures were synthesized through coprecipitation and Stöber methodresp...
متن کاملCore/shell nanofibers with embedded liposomes as a drug delivery system.
The broader application of liposomes in regenerative medicine is hampered by their short half-life and inefficient retention at the site of application. These disadvantages could be significantly reduced by their combination with nanofibers. We produced 2 different nanofiber-liposome systems in the present study, that is, liposomes blended within nanofibers and core/shell nanofibers with embedd...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2017
ISSN: 0022-3549
DOI: 10.1016/j.xphs.2016.12.031